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Note for Guidance for Food Contact Materials
Page 105 of 126
[CONSTITUENT] = set out 'monomer' or 'additive' or 'aid
to polymerisation'.
1. SCOPE:
[RANGE] =
set out numerical values of analyte concentration range
[MASS] =
set out 'g' or 'mg'.

2. PRINCIPLE:
[TECHNIQUE] =
set out principle of method used to determine analyte in
matrix, e.g. 'headspace gas chromatography' or 'solvent
extraction, then gas chromatography' or 'high performance
liquid chromatography', etc.
[STANDARD] =
set out whether an internal standard or an external standard
is used or whether standard addition is applied.

Note 1:
An internal standard should be used whenever possible and
an explanation should be offered for not using one.

[CONFIRM] =
set out what confirmation procedure is used.
3. REAGENTS:
3.1 [ANALYTE ST, FORM] = set out analyte standard used for calibration, bruto formula
inclusive
(PURITY) =
set out purity requirements, if any, of analyte standard.

3.2 [STANDARD, FORM] =
set out internal or external standard, bruto formula inclusive
(PURITY) =
set out purity requirements, if any, of internal standard, if
any.
Note 2:
In general the internal standard should contain no impurity
at > 1% by peak area or peak height which will elute at the
same retention time as that of the analyte.

3.3 [REAGENTS] =
set out chemicals, other than anal yte standard and internal
standard or external standard and solvents involved in the
procedure
(PURITY)=
set out purity requirements, if any, of reagents and solvents,
or set out 'all reagents shall be of analytical quality'.
3.4 [SOLUTIONS]=
set out solutions, concentration inclusive, involved in the
procedure, such as:
-
primary solution of analyte standard
-
dilute solution(s) of analyte standard
-
solution(s) of internal or external standard
- mobile
phase
- reagent
solutions
- etc.
(INSTRUCTIONS) =
set out detailed instructions for preparation of solutions.