- Practical Guide -
Page 49 of 153
4.2.4 Other questions on mixtures and individual components in mixture
Question: If a mixture appears in the EU positive lists, are then the individual components
Answer: Not always, because the toxicity of a substance depends on the dose ingested by
the animals examined in the toxicological test. The data obtained for a whole
mixture cannot always be extrapolated to a minor component in this mixture.
Question: If the various components of a mixture are listed individually in the positive list,
are all of their mixtures automatically authorised?
Aids to polymerisation
They are defined as "Substances, which directly influence the formation of polymers" and
constitute a separate class of substances planned to be regulated by specific rules. They
include, for example:
Chain scission reagents
Chain transfer or extending agents
Chain stop reagents
Initiators and promoters
Molecular weight regulators
Overall migration limits
The restrictions on use of plastic materials and articles are given in Art. 2.
Plastic materials and articles shall not transfer their constituents to foodstuffs in quantities exceeding 10 milligrams per square
decimetre of surface area of material or article (mg/dmē) (overall migration limit). However, this limit shall be 60 milligrams of
the constituents released per kilogram of foodstuff (mg/kg) in the following cases:
(a) Articles which are containers or are comparable to containers or which can be filled, with a capacity of not less than 500
millilitres (ml) and not more than 10 litres (1);
(b) Articles which can be filled and for which it is impracticable to estimate the surface area in contact with foodstuffs;
(c) Caps, gaskets, stoppers or similar devices for sealing.