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REF_N
CAS_N
NAME
SYNONIM
DIR
RESTRICTIONS
AND
SPECIFICATIONS
SCF
List
EFSA/SCF_OP
PL
CT
228
oral rat studies.
Needed: remaining toxicological data
depending on migration level (see SCF
guidelines) and, if migration exceeds 0.05
mg/kg, peroxisome proliferation studies and
neurotoxicity studies too.
73720
000115-96-8 Phosphoric acid,
trichloroethyl ester
DIR SML = ND (DL = 0.02
mg/kg, analytical
tolerance included)
4A
Carcinogenic to rats.
(NTP Tech. Rep. Ser. N. 391, May 1991).
+
73760
-
Phosphoric acid,
triethanol ester
9
Group R: 0.05 mg/kg b.w.
+
73840
000126-71-6 Phosphoric acid,
triisobutyl ester
6B
Group R: 0.05 mg/kg bw.
Needed: toxicological data depending on
migration level (see SCF guidelines) and, if
migration exceeds 0.05 mg/kg peroxisome
proliferation studies and neurotoxicity
studies too.
+
+
73920
000115-86-6 Phosphoric acid,
triphenyl ester
6B
Needed: toxicological data depending on
migration level (see SCF guidelines) and, if
migration exceeds 0.05 mg/kg, neurotoxicity
studies too.
+
74000
000078-42-2 Phosphoric acid, tris(2-
ethylhexyl) ester
6B
Group R: 0.05 mg/kg b.w.
Available: Ames test, 90-day and 2-year oral
mouse and rat studies.
Needed: remaining toxicological data
depending on migration level (see SCF
guidelines) and, if migration exceeds 0.05
mg/kg, peroxisome proliferation studies and
neurotoxicity studies too.
+
74010
145650-60-8 Phosphorous acid,
bis(2,4-di-tert.-butyl-6-
methylphenyl) ethyl ester
DIR SML = 5 mg/kg (sum
of phosphite and
phosphate)
3
R = 5 mg/kg of food (covering the sum of
phosphite and phosphate).

Available: migration data, three in vitro
mutagenicity tests, Ames/E. coli test with
the oxidation product, 28-day oral rat study,
90-day oral rat study, "limited" delayed
neurotoxicity study in hens.
(RIVM/TNO SDS, October 1996 =
CS/PM/2916).
+
+
74080
025448-25-3 Phosphorous acid,
6B
Group R: 0.05 mg/kg b.w.
+