background image
REF_N
CAS_N
NAME
SYNONIM
DIR
RESTRICTIONS
AND
SPECIFICATIONS
SCF
List
EFSA/SCF_OP
PL
CT
230
74720
000117-82-8 Phthalic acid, bis(2-
methoxyethyl) ester
8
Due to the lack of data according to new
SCF guidelines, the substance is transferred
from List 6B to List 8. In first instance more
data on the migration and use are needed in
order to judge if further toxicity data are also
needed.

R: 0.05 mg/kg of food (by analogy with
53860). Suspected of
embriotoxicity/teratogenicity.
Available: some studies, but inadequate.
http://www.efsa.eu.int/science/afc/afc_docu
ments/469/statement01_afc_phthalates_en1.
pdf
+
74800
068515-42-4 Phthalic acid, dialkyl
(C7-C11) esters
7
Due to the lack of data according to new
SCF guidelines, the substance is transferred
from List 6B to List 7. In first instance more
data on the migration and use are needed in
order to judge if further toxicity data are also
needed.

Group R: 0.05 mg/kg b.w.
Needed: in first instance specifications on
identity.
Toxicological data depending on migration
level (see SCF guidelines) and, if migration
exceeds 0.05 mg/kg, peroxisome
proliferation studies on specified substances.
http://www.efsa.eu.int/science/afc/afc_docu
ments/469/statement01_afc_phthalates_en1.
pdf
+
74880
000084-74-2 Phthalic acid, dibutyl
ester
2
Under re-evaluation.
------------------------------------
TDI = 0.1 mg/kg b.w.
Available: acute oral toxicity data; skin- and
eye irritation data; ADME data; 3-week oral
rat study; 4-week oral rat study; 13-week
oral rat studies; peroxisome proliferation
+
+