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REF_N
CAS_N
NAME
SYNONIM
DIR
RESTRICTIONS
AND
SPECIFICATIONS
SCF
List
EFSA/SCF_OP
PL
CT
232
ments/469/statement01_afc_phthalates_en1.
pdf
75040
-
Phthalic acid, diesters
with hexadecanol and/or
octadecanol
7
Due to the lack of data according to new
SCF guidelines, the substance is transferred
from List 2 to List 7. In first instance more
data on the migration and use are needed in
order to judge if further toxicity data are also
needed.

Group t-TDI : 0.15 mg/kg bw (with 76120).
Available: 3 months oral rat study,
teratogenicity study and Ames test negative.
(RIVM doc. 1990-09-11, CS/PM/529).
Needed: reproduction study, peroxisome
proliferation, gene mutation and
chromosome aberration in mammalian cells
in vitro.
http://www.efsa.eu.int/science/afc/afc_docu
ments/469/statement01_afc_phthalates_en1.
pdf
+
75100
-
Phthalic acid, diesters
with primary, saturated
C8-C10 branched
alcohols, more than 60%
C9.
2
Under re-evaluation.
http://europa.eu.int/comm/food/fs/sc/scf/out
50_en.pdf
+
+
75105
-
Phthalic acid, diesters
with primary, saturated
C9-C11 branched
alcohols more than 90%
C10
2
Under re-evaluation.
http://europa.eu.int/comm/food/fs/sc/scf/out
50_en.pdf
+
+
75120
000084-66-2 Phthalic acid, diethyl
ester
7
Due to the lack of data according to new
SCF guidelines, the substance is transferred
from List 2 to List 7. In first instance more
data on the migration and use are needed in
order to judge if further toxicity data are also
needed.

t-TDI: 0.2 mg/kg b.w.
Available: a 3-month oral rat study, in vitro
mutagenicity studies, i.p. teratogenicity
+
+