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REF_N
CAS_N
NAME
SYNONIM
DIR
RESTRICTIONS
AND
SPECIFICATIONS
SCF
List
EFSA/SCF_OP
PL
CT
233
studies and peroxisome proliferation studies.
(Fd. Cosm. Toxicol. 1978, 16, 415-422,
RIVM 1986, June).
Needed: reproduction and teratogenicity
study.
http://www.efsa.eu.int/science/afc/afc_docu
ments/469/statement01_afc_phthalates_en1.
pdf
75200
003648-21-3 Phthalic acid, di-n-heptyl
ester
7
Due to the lack of data according to new
SCF guidelines, the substance is transferred
from List 6B to List 7. In first instance more
data on the migration and use are needed in
order to judge if further toxicity data are also
needed.

Group R: 0.05 mg/kg b.w.
Available: Ames test.
Needed: remaining toxicological data
depending on migration level (see SCF
guidelines) and, if migration exceeds 0.05
mg/kg, peroxisome proliferation studies too.
http://www.efsa.eu.int/science/afc/afc_docu
ments/469/statement01_afc_phthalates_en1.
pdf
+
75280
000084-69-5 Phthalic acid, diisobutyl
ester
8
Due to the lack of data according to new
SCF guidelines, the substance is transferred
from List 6B to List 8. In first instance more
data on the migration and use are needed in
order to judge if further toxicity data are also
needed.

Group R: 0.05 mg/kg b.w.
Needed: toxicological data depending on
migration level (see SCF guidelines) and, if
migration exceeds 0.05 mg/kg, peroxisome
proliferation studies too.
http://www.efsa.eu.int/science/afc/afc_docu
ments/469/statement01_afc_phthalates_en1.
pdf
+
+
75360
026761-40-0 Phthalic acid, diisodecyl
D
This item is changed into a new item (see
+