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REF_N
CAS_N
NAME
SYNONIM
DIR
RESTRICTIONS
AND
SPECIFICATIONS
SCF
List
EFSA/SCF_OP
PL
CT
236
pdf
75850
-
Phthalic acid, di-n-octyl
and/or di-n-decyl and/or
n-decyl n-octyl esters
Same 67180
7
Due to the lack of data according to new
SCF guidelines, the substance is transferred
from List 3 to List 7. In first instance more
data on the migration and use are needed in
order to judge if further toxicity data are also
needed.

R: 5 mg/kg of food or food simulant.
Available: 3 mutagenicity studies negative,
3 months oral rat study, test on liver
peroxisome proliferation, migration in
aqueous food simulants only.
Remark: high migration into fatty food is
likely.
(RIVM report 1995-09-04 (=CS/PM/2655)).
http://www.efsa.eu.int/science/afc/afc_docu
ments/469/statement01_afc_phthalates_en1.
pdf
+
75920
000119-06-2 Phthalic acid, di-n-
tridecyl ester
7
Due to the lack of data according to new
SCF guidelines, the substance is transferred
from List 6B to List 7. In first instance more
data on the migration and use are needed in
order to judge if further toxicity data are also
needed.

Group R: 0.05 mg/kg b.w.
Available: Ames test.
Needed: remaining toxicological data
depending on migration level (see SCF
guidelines) and, if migration exceeds 0.05
mg/kg, peroxisome proliferation studies too.
http://www.efsa.eu.int/science/afc/afc_docu
ments/469/statement01_afc_phthalates_en1.
pdf
+
76000
-
Phthalic acid, mixed
esters with butyl
glycolate and alcohols,
aliph.,monoh., (C1-C4)
8
Due to the lack of data according to new
SCF guidelines, the substance is transferred
from List 9 to List 8. In first instance more
data on the migration and use are needed in
order to judge if further toxicity data are also
+