background image
REF_N
CAS_N
NAME
SYNONIM
DIR
RESTRICTIONS
AND
SPECIFICATIONS
SCF
List
EFSA/SCF_OP
PL
CT
63
glycol (hydrolysis product)
http://www.efsa.eu.int/science/afc/afc_opini
ons/190/opinion_afc_06_en1.pdf
http://europa.eu.int/comm/food/fs/sc/scf/out
141_en.pdf
16960
000107-15-3 Ethylenediamine
Same 15272
and 53540
DIR SML = 12 mg/kg
2
TDI: 0.2 mg/kg b.w.
Two 90-day oral rat studies.
(ICI report, April 1975).
+
+
16990
000107-21-1 Ethyleneglycol
Same 16778
and 53650
DIR SML(T) = 30 mg/kg
(3)
2
Group TDI = 0.5 mg/kg b.w. (with
diethyleneglycol).
See references for diethyleneglycol.
+
+
16993
000111-76-2 Ethyleneglycol
monobutyl ether
Same 53765
2
Group t-TDI : 0.05 mg/kg b.w. (with
15780=48050, 16993=53765, 16996=53820,
16999, 17002=53860, 30015, 30120, 30200,
48030).
See references for 16996.
+
16996
000110-80-5 Ethyleneglycol
monoethyl ether
Same 53820
2
Group t-TDI : 0.05 mg/kg b.w. (with
15780=48050, 16993=53765, 16996=53820,
16999, 17002=53860, 30015, 30120, 30200,
48030, 48050) pending evaluation of NTP
rat and mouse studies.
Several short term oral rat and dog studies,
reproduction and teratogenicity studies.
Carcinogenicity studies in mice and rats not
reported. Mutagenicity studies inadequate.
(RIVM summary, March 1991
(=CS/PM/922) and RIVM SDS, July 1996
(= CS/PM/2916).
+
17005
000151-56-4 Ethyleneimine
Same 53950
DIR SML = ND (DL = 0.01
mg/kg).
4A
Highly toxic by all exposure routes.
Carcinogenic for mice orally.
(IARC Monographs Vol 9, p. 37, Lyon
1975).
+
+
17020
000075-21-8 Ethylene oxide
DIR QM = 1 mg/kg in FP
4A
Strongly mutagenic in several studies.
Induces forestomach tumours in rats after
oral administration.
(Brit. J. Cancer, 1982, 46, 924; IARC
Monographs Vol. 11 and Suppl. 4, Lyon
1976 and 1982; Toxicity of ethylene oxide
and its relevance to man. ECETOC,
+
+