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REF_N
CAS_N
NAME
SYNONIM
DIR
RESTRICTIONS
AND
SPECIFICATIONS
SCF
List
EFSA/SCF_OP
PL
CT
89
22190
002163-42-0 2-Methyl-1,3-
propanediol
3
R = 5 mg/kg of food.
Available: Worst case migration < 0.6
mg/kg food; log Po/w; three (negative)
mutagenicity studies; 14-day oral rat study;
90-day oral rat study.
(RIVM/ISS/TNO SDS, April 1997 =
CS/PM/2998/22190).
(Adopted at 111th SCF meeting (18-19
March 1998)).
http://europa.eu.int/comm/food/fs/sc/scf/out
10_en.pdf
+
22210
000098-83-9 alpha-Methylstyrene
DIR
3
0.05 mg/kg food
http://www.efsa.eu.int/science/afc/afc_opini
ons/675/afc_opinion20_ej109_list5_en1.pdf
http://europa.eu.int/comm/food/fs/sc/scf/out
10_en.pdf
+
+
22240
000622-97-9 p-Methylstyrene
Same 26292
D
6A
+
+
22242
006144-04-3 alpha-Methylstyrene
dimer
D
+
22270
000107-25-5 Methyl vinyl ether
D
7
Needed: hydrolysis data.
+
22300
000078-94-4 Methyl vinyl ketone
D
6A
+
22330
001822-74-8 Methyl vinyl thioether
D
6A
+
22330/50 -
Mixture of (80%) 2,4-
diamino-3,5-
diethyltoluene and (20%)
2,6-diamino-3,5-
diethyltoluene
7
SCF_list: 7
Needed data or information:
- an in vivo/in vitro rat liver UDS on a
representative batch
- an explanation for the contradictory results
observed in the Ames test.
See SCF evaluation in the website:
http://europa.eu.int/comm/food/fs/sc/scf/out
140_en.pdf
+
22331
025513-64-8 Mixture of (35-45%
w/w) 1,6-diamino-2,2,4-
trimethylhexane and (55-
65% w/w)1,6-diamino-
2,4,4-trimethylhexane
Same 15355
DIR QMA = 5 mg/6 dmē
3
Re-evaluation to align this evaluation with
other evaluations done by the SCF.
R = 5 mg/6 dm2.
Remark for Commission: A QM would be
indicated. The choice of a QM instead of
SML is due to the reactivity of the substance
+
+