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1970: plasticizers are identified in culture medium of PVC Petri plates
1971: DEHP in transfused blood, it is demonstrated that DEHP originates from plastics bags used to
store blood
1974: In USA, experts estimate that ingested quantities have no public concern
1987: In Startin (UK), the average intake of DEHA is of 16 mg/person/day
1990: Introduction of mixtures adipates - polyadipates
1996: Polymeric plasticizers are proposed for food contact in EU (authorized in 1999)
1998: The average intake of DEHA is of 3 mg/person/day
WHY TO REGULATE ?
HISTORY OVERVIEW
Bis(2-ethylhexyl)phtalate=DEHP
Bis(2-ethylhexyl)adipate=DEHA
Tributyl-acetyl citrate