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Tox ic ology Tes ting
Tox ic ology Tes ting
R egimen:
R egimen:
Minimum Toxicity Tests
Exposure Level
(micrograms/person/day)
Ames Assay
1.5
Mouse Lymphoma Assay or
In vitro Chromosome Aberration test
1.5
In vivo Chromosome Aberration Test
150
Subchronic Toxicity Test with Rodents
150
Subchronic Toxicity Test with Non-rodents 150
Repro study w/ teratology phase
3000
One-Yr toxicity test with non-rodents
3000
Carcinogenicity study with rodents
3000
Chronic tox/ carcinogenicity study with
rodents
3000